Guest Blog by: Joi Gilliam
Over the years, there have been many theories and techniques for antidepression therapy. Although medication and psychotherapy are two of the most popular techniques, there is still little that is known about effectively treating depression. Many patients will spend years trying out different medications that might help, but do not fully treat the symptoms of depression. Surprisingly, the answer to antidepressant therapy may lie in folic acid treatments.
While there is still much that is unknown about depression, doctors do know that depression is caused by an imbalance of serotonin, norepinephrine, and dopamine. These neurotransmitters are used to regulate different moods, and many patients will need to treat their depression by addressing one or two of these chemical imbalances. Patients with major depressive symptoms show a folate deficiency, which can directly result in these chemical imblances. Additionally, folic acid deficiency is genetic and for a number of patients, this deficiency is a contributing factor in depression. The brain uses folate to help regulate neurotransmitter levels in the brain. Current anti-depression treatments attempt to treat the neurotransmitter imbalances by simply replacing these chemicals. However, this is ineffective because it does not provide a natural balance for those neurotransmitters. For many patients, these treatments work better when used in conjunction with L-methylfolate, which is a metabolized form of folate. L-methylfolate is the only form of folic acid that can penetrate the blood brain barrier. Once this supplement is introduced into the brain, it can better regulate those neurotransmitters that are causing depression by naturally allowing the brain to create a better balance.
Two recent studies have shown that patients being treated with L-methylfolate are two times more likely to experience asignificant improvement in their antidepressant treatment. Even patients that do not currently show depressive symptoms can benefit from an L-methylfolate treatment, since patients with a folic acid deficiency are more likely to later develop depression.